Self-organization of protein systems

We study how protein systems self-organize into complex patterns in space and time.

Instead of looking at these phenomena in an intact cell, our group rebuilds cellular processes from purified components in vitro. We are particularly interested in the mechanism of Bacterial cell division and Small GTPase signaling.

We combine Biochemistry, Fluorescence Microscopy, Quantitative Image Analysis and Microfabrication in highly interdisciplinary projects. With this approach, we bridge the gap between what we know about the molecular level and what we can observe on the cellular scale.

Our goal is to understand the non-equilibrium properties of protein self-organization as well as the underlying molecular mechanisms which eventually give rise to the living cell. 

The Loose Lab is part of ISTA, located in Klosterneuburg, close to Vienna, Austria.